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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RFC1
All Species:
9.09
Human Site:
S520
Identified Species:
18.18
UniProt:
P35251
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35251
NP_002904.3
1148
128255
S520
G
K
R
K
I
S
P
S
K
K
E
S
E
S
K
Chimpanzee
Pan troglodytes
XP_001140765
1148
128250
S520
G
K
R
K
I
S
P
S
K
K
E
S
E
S
K
Rhesus Macaque
Macaca mulatta
XP_001091287
1148
128475
S520
G
K
R
K
I
S
P
S
K
K
E
S
E
S
K
Dog
Lupus familis
XP_536259
1145
128125
P517
Q
G
K
R
K
I
S
P
T
K
K
E
S
E
S
Cat
Felis silvestris
Mouse
Mus musculus
P35601
1131
125967
P517
Q
G
K
R
K
I
S
P
A
K
K
E
S
E
S
Rat
Rattus norvegicus
NP_445999
1131
125770
P515
Q
G
K
R
K
L
S
P
T
K
R
E
L
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512744
1233
136122
P603
Q
G
K
R
K
A
T
P
N
R
K
E
S
G
S
Chicken
Gallus gallus
NP_001006456
1147
128454
P517
S
G
K
R
N
F
S
P
L
K
R
E
A
D
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P35600
986
108596
L416
R
T
A
D
L
K
T
L
D
V
V
G
M
A
W
Honey Bee
Apis mellifera
XP_397246
911
103001
M341
E
I
E
T
S
L
K
M
S
P
Q
K
K
E
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797949
906
99249
I336
T
F
V
L
T
G
V
I
E
Y
F
D
K
D
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38630
861
94885
V291
H
L
E
R
D
N
V
V
R
E
E
D
K
L
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.3
89.3
N.A.
82.4
81.3
N.A.
67.4
68.9
N.A.
N.A.
N.A.
39.9
36.2
N.A.
38
Protein Similarity:
100
99.6
98.5
93.7
N.A.
89.5
88.5
N.A.
77.2
79.6
N.A.
N.A.
N.A.
55.9
53.6
N.A.
52.2
P-Site Identity:
100
100
100
6.6
N.A.
6.6
6.6
N.A.
0
6.6
N.A.
N.A.
N.A.
0
0
N.A.
0
P-Site Similarity:
100
100
100
26.6
N.A.
26.6
20
N.A.
33.3
26.6
N.A.
N.A.
N.A.
13.3
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
9
0
0
9
0
0
0
9
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
9
0
0
0
9
0
0
17
0
17
0
% D
% Glu:
9
0
17
0
0
0
0
0
9
9
34
42
25
34
0
% E
% Phe:
0
9
0
0
0
9
0
0
0
0
9
0
0
0
0
% F
% Gly:
25
42
0
0
0
9
0
0
0
0
0
9
0
9
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
25
17
0
9
0
0
0
0
0
0
0
% I
% Lys:
0
25
42
25
34
9
9
0
25
59
25
9
25
0
25
% K
% Leu:
0
9
0
9
9
17
0
9
9
0
0
0
9
9
0
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
0
9
0
0
% M
% Asn:
0
0
0
0
9
9
0
0
9
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
25
42
0
9
0
0
0
0
9
% P
% Gln:
34
0
0
0
0
0
0
0
0
0
9
0
0
0
9
% Q
% Arg:
9
0
25
50
0
0
0
0
9
9
17
0
0
0
9
% R
% Ser:
9
0
0
0
9
25
34
25
9
0
0
25
25
25
25
% S
% Thr:
9
9
0
9
9
0
17
0
17
0
0
0
0
0
0
% T
% Val:
0
0
9
0
0
0
17
9
0
9
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% W
% Tyr:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _